Benzamide, 5-amino-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]-
GRL0617
CAS: 1093070-16-6
Molecular Formula: C20H20N2O
Benzamide, 5-amino-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]- - Names and Identifiers
| Name | GRL0617 |
| Synonyms | GRL0617 GRL-0617 (GRL0617 5-Amino-2-methyl-N-(1R-naphthalen-1-yl-ethyl)benzamide Benzamide, 5-amino-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]- |
| CAS | 1093070-16-6 |
Benzamide, 5-amino-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]- - Physico-chemical Properties
| Molecular Formula | C20H20N2O |
| Molar Mass | 304.39 |
| Density | 1.168±0.06 g/cm3(Predicted) |
| Boling Point | 514.9±50.0 °C(Predicted) |
| Solubility | Soluble in DMSO |
| Appearance | solid |
| Color | Beige |
| pKa | 14.26±0.46(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Stability | Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
| Use | GRL0617 is a potent, selective and competitive non-covalent inhibitor of PLpro/deubiquitinase SARS-CoV, with IC50 value of 0.6 μM and Ki value of 0.49 μM. |
Benzamide, 5-amino-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]- - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.285 ml | 16.426 ml | 32.853 ml |
| 5 mM | 0.657 ml | 3.285 ml | 6.571 ml |
| 10 mM | 0.329 ml | 1.643 ml | 3.285 ml |
| 5 mM | 0.066 ml | 0.329 ml | 0.657 ml |
Last Update：2024-01-02 23:10:35
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